Mother and daughter sporocysts and xiphidiocercariae develop in Helisoma trivolvis. Cercariae penetrate tadpoles of Rana pretiosa and small A. tigrinum larvae in which they encyst. The adult develops in the anterior small intestine of A. tigrinum after ingestion of an infected 2nd intermediate host. The life cycle of C. salamandrus is compared with C. americanus from Rana clamitans. C. salamandrus is described as a new species on the basis of cercarial and adult morphology, and the failure to achieve cross-infections in the respective definitive hosts for C. americanus and C. salamandrus.